International Stem Cell Corp., a
California-based biotechnology company developing novel stem cell based
therapies and biomedical products, today reported that the Japan Patent Office
has issued ISCO’s patent covering methods of making a bank of human stem cells
from parthenogenetically activated eggs. This win significantly bolsters the
company’s intellectual property position and ability to form partnerships in
Japan.
“The new patent strengthens our
position as a leader in regenerative medicine. With the potential to avoid one
of the fundamental problems of tissue and cell therapy, immune-matching, and
having been shown to be more genetically stable than iPS cells, our human
parthenogenetic stem cells hold potential significant therapeutic value,” said
Ruslan Semechkin, PhD, ISCO’s chief scientific officer. “The new patent also
extends the geographic reach of our broad IP portfolio beyond the US and EU
making us a more attractive partner for Japanese pharmaceutical companies.”
ISCO’s patent covers a new method
of creating stem cells that combine many of the benefits of embryonic stem
cells with induced pluripotent stem cells and can be used to generate virtually
unlimited quantities of human cells. The company is currently using this
technology to develop treatments for a number of indications where cell therapy
has been demonstrated to be effective but there is insufficient supply of safe,
functional cells. Preclinical safety and efficacy data from the company’s
Parkinson’s disease program was recently presented at the Society for
Neuroscience annual meeting, and a Phase I/IIa clinical study in Parkinson’s
disease is anticipated to begin in the near future.
Along with ISCO’s substantial
collection of US patents, and the recently announced resolution by the European
Union Court of Justice in favor of the company’s EU patent applications, this
new Japanese patent provides intellectual property protection and licensing
opportunities for ISCO in the three largest healthcare markets.
For more information, visit
www.internationalstemcell.com
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