Thursday, May 22, 2014

VistaGen Therapeutics, Inc. (VSTA) Joins HESI Cardiac Safety Committee, Sees Collaborative Benefits

VistaGen Therapeutics, a biotechnology company applying pluripotent stem cell technology for drug rescue and regenerative medicine, reports that it is now a member of the Cardiac Safety Technical Committee, Cardiac Stem Cell Working Group, and Proarrhythmia Working Group of the Health and Environmental Sciences Institute (HESI).

Using mature cardiomyocytes (heart cells) differentiated from human pluripotent stem cells, VistaGen developed its CardioSafe 3D™ bioassay system to predict the in vivo cardiac effects, both toxic and non-toxic, of small molecule drug candidates with greater speed and precision than the traditional, surrogate safety models most often used in drug development. The company’s pluripotent stem cell-derived heart cells and CardioSafe 3D are vital components of its Human Clinical Trials in a Test Tube™ platform and drug rescue programs.

Ralph Snodgrass, Ph.D., VistaGen’s president and chief scientific officer commented, “We look forward to collaborating with leading pharmaceutical, biotechnology, academic, and regulatory members of the HESI’s Cardiac Safety Technical Committee, and related working groups, to help advance, among other goals, the FDA’s CIPA initiative, which is focused on developing innovative preclinical systems for cardiac safety assessment during drug development.”

HESI, a global branch of the International Life Sciences Institute (ILSI), boasts a membership roll that includes most of the world’s largest biotechnology and pharmaceutical companies for which it provides an international forum to advance the understanding of scientific issues related to human health, toxicology, risk assessment, and the environment. ILSI is a nonprofit, worldwide organization whose mission is to provide science that improves human health and well-being and safeguards the environment.

Operating from its headquarters in San Francisco, California, VistaGen contends that better cells lead to better medicine and that the key to making better cells is controlling with precision the differentiation of human pluripotent stem cells, which are the base cells of the human body.

For more information on the company visit www.VistaGen.com/

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