Human pluripotent stem cells are a type of cell that is
self-replicating. In simple terms, they clone themselves. These are typically
derived from human embryos and have the possibility to grow into virtually any
type of cell in the body. The first type of pluripotent stem cells were
embryonic stem cells (ESC). Unfortunately, there are moral issues associated
with these, since their creation involves the destruction of a human embryo.
This said, a new type of pluripotent stem cell has been pioneered. These come
from unfertilized eggs being “tricked” into developing as embryos without being
fertilized. These stem cells do not involve destroying an embryo, and therefore
avoid the associated moral issues. These new stem cells are called human
parthenogenetic stem cells (hPSC).
Human parthenogenetic stem cells not only erase the moral
issues associated with ESC, they also maintain many of the advantages. Some of
these advantages include immune matching, pluripotency, proliferation, genetic
reprogramming, and the ability to use stem cells to cure genetic diseases.
Pluripotency is when the stem cells can change into the full range of
specialized stem cell types, while immune matching is when cells derived from
stem cells match other patients to avoid rejection problems. Proliferation is
when the stem cells easily expand, and genetic reprogramming is whether or not
the source of the stem cells have been modified by external factors.
International Stem Cell Corp. (OTCQB: ISCO) is a
biotechnological company that started developing this new type of stem cell
derived from unfertilized eggs in order to help treat severe diseases of the
nervous system, liver and eyes. Some of the diseases that are in the process of
being treated by this new line of stem cells include Parkinson’s disease,
ischemic strokes, metabolic liver diseases, retinal blindness, and corneal
blindness, among others. After showing significant results in earlier
therapies, ISCO has progressed to Phase I clinical trials for the treatment of
Parkinson’s disease.
For more information, visit www.internationalstemcell.com
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