BrainStorm Cell Therapeutics, a biotech company engaged in the development adult stem cell technologies for neurodegenerative diseases, reports that it will initiate a pre-clinical study for multiple sclerosis (MS) at the Hebrew University Hadassah Medical Center’s SPF-grade animal laboratory in Jerusalem.
Based on favorable pre-clinical data published by BrainStorm chief scientist Professor Daniel Offen of Tel Aviv University, the company says it will conduct additional studies using the Experimental Autoimmune Encephalomyelitis (EAE) animal model to evaluate MS as an additional indication for its NurOwn™ technology.
NurOwn induces bone marrow-derived mesenchymal stem cells (MSC) to secrete high levels of neurotrophic factors to protect existing motor neurons, promotion of motor neuron growth, and re-establish nerve-muscle interaction.
Professor Dimitrios Karussis and Dr. Ibrahim Kassis, who have published extensively on pre-clinical research using the EAE model, will be the principal investigators of BrainStorm’s upcoming study.
The study was approved by the Institutional Animal Care and Use Committee (IACUC) of the Hebrew University.
Professor Karussis, a key opinion leader in the field of MS, is head of the multi-disciplinary MS Clinic and Center at Hadassah, member of the European Steering Committee for Bone Marrow Transplantation in MS, and a member of the Executive Board and Scientific Committee of the European School of Neuroimmunology (ESNI). He is also former board member of the European Council and Committee for Treatment and Research in MS, and has been the principal investigator of several multi-national clinical trials in MS conducted by global pharmaceutical companies.
For more information, visit www.brainstorm-cell.com
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