Yesterday, International Stem Cell
Corp., a California-based biotechnology company developing novel stem cell
based therapies and biomedical products, announced the completion of a recently
discovered compound’s clinical testing. This compound is expected to be
utilized in skin care products marketed by the company’s wholly-owned
subsidiary Lifeline Skin Care, Inc.
Topical treatment with the
compound showed significant (p<0.01) improvement in skin elasticity and
decrease in skin roughness in all subjects 4 and 8 weeks after the start of the
study. In addition, the compound-treated group outperformed not only the
baseline, but also the Retinol treated group. There were no adverse events
reported in the compound-treated group, such as skin irritation, which has been
reported as a common side effect of Retinol treatment.
Prior to the clinical study, the
compound was tested on different in vitro models: normal human keratinocytes,
fibroblasts and 3D model of human skin. In all these models, the recently
discovered compound induced up to twice the production of elastin and collagen
compared to Retinoic Acid (the active form of Retinol) with none of its toxic
characteristics.
The launch of the compound-based
products is expected this year. Currently Lifeline markets its stem cell-based
skin care in the US and Asia via professional and on-line retail channels
(www.lifelineskincare.com). The company believes that these new compound-based
products will not only allow it to increase sales and profit margins in its
existing markets, but also will allow it to enter the European “high-tech” skin
care market.
For more information on
International Stem Cell Corp., visit www.internationalstemcell.com
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