Rainbow Coral’s partner, Nano3D Biosciences (n3D), is the creator of one of the newest 3D cell culturing technology on the market. Cells grown in 2D mono-layers simply do not replicate the complex interactions and architecture found in living organisms, which limits their use in basic life science research, toxicity testing, and drug discovery. n3D’s Bio-Assembler brings the simplicity of 2D culturing to 3D.
The company’s Bio-Assembler is as simple as standard 2D techniques and faster than any other 3D cell culturing product currently available. Preparation time and cell manipulation requirements are equivalent to 2D culture. In fact, there are only two additional steps that differentiate the Bio-Assembler’s innovative 3D cell culturing process from 2D cell culturing: (1) Adding the Nanoshuttle to cells prior to levitation, and (2) Placing the magnetic drive on top of the cell culture plate.
With the Bio-Assembler, easy-to-use reagents deliver biocompatible magnetic nanoparticles to cells, and magnetic forces gently levitate and guide cells together to quickly induce cell-cell interactions. It’s a process that mimics the in vivo environment, yet operates in standard petri dishes with virtually any cell and media type. It’s compatible with co-culturing, and standard imaging and diagnostic techniques.
There are important advantages offered by n3D’s cell culturing system:
• Rapid formation of 3D structures and cell-cell interactions
• More accurate representation of in vivo tissue
• Compatibility with virtually any cell type, including primary and stem cells
• Unique capability for moving and shaping tissue, applicable to invasion studies and tissue engineering
• Compatibility with any media type, standard culturing protocols, and diagnostic techniques
The company’s Bio-Assembler system works with virtually all cell types, including primary lung cells, glioblastoma cells, HUVEC cells, neural stem cells, liver cells, and breast cells. It also works with all standard protocols and diagnostics, including Fixing Tissue, Immunohistochemistry (Paraffin Embedded), Immunohistochemistry (Non-Embedded/Whole Mount), High Resolution Imaging, and Levitating Suspended Cells.
The technology is a game changer, to the extent that it was even written up in Nature, the world’s premiere science journal.
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