Along with the growing development of stem cell technology as a tool for both research and therapeutics, stem cell banking has become more widespread, both in the U.S. and around the world. The preservation of stem cells, whether sourced and preserved for an individual family or the general population, is seen as an important way to cost effectively facilitate the availability of stem cells, and different stem cell banks have been set up to hold stem cells of different types.
One stem cell bank, UniStemCell bank, is unique in the world, because it holds the life science industry’s first collection of non-embryonic histocompatible human stem cells, available for research and commercial use. International Stem Cell Corporation’s proprietary technique for creating such histocompatible stem cells, a process called parthenogenesis, uses unfertilized human eggs. By so doing, the process avoids the controversy of using stem cells from human embryos, and also results in the stem cells inheriting a duplicate set of human leukocyte antigen genes. This significantly reduces the possibility of the derived cells being rejected by an individual’s immune system, making a single cell line suitable for treating millions of individuals. A relatively small number of such stem cell lines could be enough to provide immune-matched cells to a significant percentage of the world’s population.
For ISCO, revenue could be generated from universal stem cell bank franchises across populations and scientists accessing these lines. This will provide additional validation of the hpSC lines as they are tested and developed by others across a range of potential applications. Later, the arrangement will provide the company with royalty from sales of each successful hpSC-derived cellular therapeutic.
For additional information on ISCO, visit the company’s website at www.internationalstemcell.com
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