Pressure BioScience (OTCQB: PBIO), a leader in the
development and sale of broadly enabling, pressure-based instruments,
consumables and platform-technology solutions to the worldwide life sciences
and other industries, today announced that the combination of PBIO’s patented
Pressure Cycling Technology (“PCT”) with RedShiftBio’s proprietary Microfluidic
Modulation Spectroscopy (“MMS”) has resulted in a powerful new platform for
biotherapeutic drug development (“PCT-enhanced MMS”). PBIO believes combining
both platforms enables for the rigorous investigation of protein structure and
stability in a highly efficient workflow that can be crucial in drug development.
Per the release, the collaboration should result in faster development of new
drugs as well as improvement in the quality of drugs coming onto the market.
“Our collaboration with RedShiftBio takes advantage of our ability to
manipulate protein structure with high pressure and RedShiftBio’s precise
analytical platform that reports subtle changes in the three-dimensional
structure of protein molecules that could lead to protein aggregation.
Unfortunately, aggregated protein biologics could train a patient’s immune
system to recognize and eliminate the drug, so finding appropriate formulations
to prevent aggregation is a major task in biopharmaceutical drug development.
Moreover, MMS will help us to understand protein folding kinetics in our
BaroFold platform, which uses high pressure to shape recombinant proteins into
their active and stable conformations in biomanufacturing process development,”
Alexander V. Lazarev, Ph.D., Chief Science Officer of PBIO stated in the news
release.
To view the full press release, visit http://ibn.fm/rvqFS
About Pressure BioSciences Inc.
Pressure BioSciences is a leader in the development and sale
of innovative, broadly enabling, pressure-based solutions for the worldwide life-sciences
industry. The company’s products are based on the unique properties of both
constant (i.e., static) and alternating (i.e., pressure-cycling technology, or
“PCT”) hydrostatic pressure. PCT is a patented, enabling technology platform
that uses alternating cycles of hydrostatic pressure between ambient and
ultra-high levels to safely and reproducibly control bio-molecular interactions
(e.g., cell lysis, biomolecule extraction). PBIO’s primary focus is in the
development of PCT-based products for biomarker and target discovery, drug
design and development, biotherapeutics characterization and quality control,
soil and plant biology, forensics and counter-bioterror applications.
Additionally, major new market opportunities have emerged in the use of its
pressure-based technologies in the following areas: (1) the use of its recently
acquired, patented technology from BaroFold Inc. (the “BaroFold” technology) to
allow entry into the biopharma contract services sector, and (2) the use of its
recently patented, scalable, high-efficiency, pressure-based Ultra Shear
Technology (“UST”) platform to (i) create stable nanoemulsions of otherwise
immiscible fluids (e.g., oils and water) and (ii) prepare higher-quality,
homogenized, extended shelf-life or room-temperature, stable, low-acid liquid
foods that cannot be effectively preserved using existing nonthermal
technologies. For more information, visit the company’s website at www.PressureBiosciences.com.
NOTE TO INVESTORS: The latest news and updates
relating to PBIO are available in the company’s newsroom at http://ibn.fm/PBIO
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