BriaCell Therapeutics (OTCQB: BCTXF) (TSX.V: BCT), an
immuno-oncology focused biotechnology company, is continuing its progression of
Bria-IMT for the treatment of advanced breast cancer. An article discussing the
company reads, “The Bria-IMT phase I/IIa monotherapy study involved 23 patients
who were very heavily pre-treated (a median of four previous systemic therapy
regiments per patient). The treatment with Bria-IMT was well-tolerated, with
minor local irritation at the injection site being reported as the most common
adverse effect. … More importantly, Bria-IMT contributed to tumor shrinkage in
three of the patients. The top respondent previously received seven rounds of
chemotherapy and had tumor metastases at various sites. The patient’s
three-month follow-up showed shrinkage in all 20 metastatic formations in the
lungs. After six months, the response was still maintained. Two other patients
also showed tumor reduction. All of the patients with tumor reduction matched
Bria-IMT at one or more HLA types, validating BriaCell’s approach to selecting
patients most likely to respond (BriaDx). Biological activity was observed in
several other of the patients, and there was a noted decrease in circulating
cancer-associated cells.”
To view the full article, visit http://ibn.fm/jP5RH
About BriaCell
BriaCell is an immuno-oncology focused biotechnology company
developing targeted and safe approaches for the management of cancer. BriaCell
is currently conducting a Phase I/IIa clinical trial of Bria-IMT, its lead
candidate, in a combination study with pembrolizumab [Keytruda; manufactured by
Merck & Co., Inc.] or ipilimumab [Yervoy; manufactured by Bristol-Myers
Squibb Company]. The combination study is listed in ClinicalTrials.gov as
NCT03328026. BriaCell is developing Bria-OTS, an off-the-shelf personalized
immunotherapy, for advanced breast cancer. Bria-OTS immunotherapy treatments
are personalized to match the patient without the need for personalized
manufacturing. Bria-OTS, which is expected to cover over 90 percent of the
patient population, is designed to produce a potent and selective immune
response against the cancer of each patient while eliminating the time,
expense, and complex manufacturing logistics associated with other personalized
immunotherapies. For more information, visit the company’s website at www.BriaCell.com.
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