Biotechnology company CytoDyn (OTCQB: CYDY) recently
reported significant developmental progress during phase 3 trials for its PRO
140 monotherapy for human immunodeficiency virus (HIV) after observing enhanced
response rates at higher doses of the treatment (http://ibn.fm/yuYub). An article discussing the company’s
progress reads: “The dosage increase will apply to all newly enrolled patients
but also to current trial participants who failed to maintain suppressed HIV
viral load on a lower dose. Approximately 70 percent of trial participants who
started PRO 140 at 525 mg and have been undergoing treatment between one and
nine months are achieving HIV viral load suppression, according to CytoDyn
President and CEO Nader Pourhassan, Ph.D. Increasing the dosage further, to 700
mg per week, is expected to have even better results. “This IRB decision is
exciting for patients, our Company and our shareholders, given the potential
for a higher patient response rate with PRO 140 as a single agent at the 700 mg
dose level,” Pourhassan explained in a news release.”
To view the full article, visit http://ibn.fm/FIku3
About CytoDyn
CytoDyn is a biotechnology company focused on the clinical
development and potential commercialization of humanized monoclonal antibodies
for the treatment and prevention of HIV infection. The company has one of the
leading monoclonal antibodies under development for HIV infection, PRO 140,
which has completed phase 2 clinical trials with demonstrated antiviral activity
in humans and is currently in phase 3 development. PRO 140 blocks the HIV
co-receptor CCR5 on T cells, which prevents viral entry. Clinical trial results
thus far indicate that PRO 140 does not negatively affect the normal immune
functions that are mediated by CCR5. Results from seven phase 1 and phase 2
human clinical trials have shown that PRO 140 can significantly reduce viral
burden in people infected with HIV. A recent phase 2b clinical trial
demonstrated that PRO 140 can prevent viral escape in patients during several
months of interruption from conventional drug therapy. CytoDyn intends to
continue to develop PRO 140 as a therapeutic anti-viral agent in persons
infected with HIV and to pursue non-HIV, inflammatory indications where CCR5
and its ligand CCL5 may be involved. For more information, visit the company’s
website at www.Cytodyn.com.
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