The 1966 science fiction movie Fantastic Voyage tells the futuristic story of an attempt to save a man’s life by using a new miniaturization technology. In the movie, a specially designed submarine and crew are reduced in size to a microscopic dot, allowing scientists to inject them into the patient where they are able to destroy a blood clot and save the patient’s life. An incredible story, but one with parallels to the research and development being carried out by New Jersey based biotechnology company Advaxis.
Advaxis is developing ways to use tiny bio-engineered bacteria to manipulate the human immune system as a unique way of fighting cancer and infectious diseases, like training millions of micro-surgeons to operate deep inside the body. The company’s immunotherapy platform technology is based on the use live, attenuated bacteria, bio-engineered to secrete an antigen/adjuvant fusion protein that redirects the powerful immune response all human beings have to the bacteria to attack the cancer itself.
Over 15 distinct constructs are in various stages of development, either developed directly by Advaxis or through collaboration with recognized centers of excellence around the country and the world. Advaxis’ first construct, ADXS-HPV, is being evaluated in 4 Phase 2 clinical trials for HPV associated diseases (CIN 2/3, cervical cancer, head and neck cancer). In 2012, Advaxis won an award for the Best Therapeutic Vaccine at the 5th Annual Vaccine Industry Excellence Awards in Washington, DC.
This week, Advaxis Chairman and CEO, Tom Moore, presented at the 6th Annual OneMedForum, a gathering of leading investors and management for some of the most promising emerging life science companies in Asia and North America, where he spoke about developing the next generation of cancer immunotherapies. It was an important opportunity to make the company’s case to investors, and it didn’t hurt that ADXS shares have recently jumped over 80% after getting coverage from the GotStockTips SMS alert service.
For additional information, visit www.Advaxis.com
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